Illudin S( —— )

Catalog No. M33870 CAS No. 1149-99-1

Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Illudin S
Note

Research use only, not for human use.
Brief Description

Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
Description

Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells.
In Vitro

Illudin S (0-0.26 nM; 24-72 hours) shows cytotoxicity in human fibroblasts.Cell Viability Assay Cell Line:Human fibroblasts Concentration:0-0.26 nM Incubation Time:24 hours, 72 hours Result:Decreased cell survival.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

DNA Alkylator/Crosslinker | Apoptosis | Antifungal
Research Area

——
Indication

——

Chemical Information

CAS Number

1149-99-1
Formula Weight

264.32
Molecular Formula

C15H20O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (189.16 mM; Ultrasonic )
SMILES

CC1=C2[C@@H](O)[C@](C)(CO)C=C2C(=O)[C@](C)(O)C11CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hansruedi Glatt, et al. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol . 2014 Jan;88(1):161-9.?

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